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DeCS
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Descritor Inglês:
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Integrin alpha6beta1
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Descritor Espanhol:
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integrina alfa6beta1
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Descritor Português:
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Integrina alfa6beta1
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Sinônimos Inglês:
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CD49f CD29
CD49f-CD29
Glycoprotein I'c-IIa, Platelet
I'c-IIa, Platelet Glycoprotein
Integrin alpha(6)beta(1)
Integrin alpha6Abeta1
Integrin alpha6Bbeta1
Integrin, alpha6beta1
Platelet Glycoprotein I'c IIa
Platelet Glycoprotein I'c-IIa
VLA 6
VLA-6
alpha 6 beta 1 Integrin
alpha6Abeta1, Integrin
alpha6Bbeta1, Integrin
alpha6beta1 Integrin
alpha6beta1, Integrin
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Categoria:
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D12.776.395.550.625.419
D12.776.543.550.625.419
D12.776.543.750.705.408.850.674
D12.776.543.750.705.675.514
D12.776.543.750.705.876.500
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Definição Inglês:
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A cell surface receptor mediating cell adhesion to the EXTRACELLULAR MATRIX and to other cells via binding to LAMININ. It is involved in cell migration, embryonic development, leukocyte activation and tumor cell invasiveness. Integrin alpha6beta1 is the major laminin receptor on PLATELETS; LEUKOCYTES; and many EPITHELIAL CELLS, and ligand binding may activate a number of signal transduction pathways. Alternative splicing of the cytoplasmic domain of the alpha6 subunit (INTEGRIN ALPHA6) results in the formation of A and B isoforms of the heterodimer, which are expressed in a tissue-specific manner. |
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Nota Histórica Inglês:
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2003; use INTEGRIN ALPHA6BETA1 (NM) 1992-2002
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Qualificadores Permitidos Inglês:
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Número do Registro:
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37451
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Identificador Único:
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D039121
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Ocorrência na BVS:
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Similar:
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DeCS
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